11 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis ... and Primary Causes ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... → Systematic screening ... #treatment #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #secondary #systemic ... #Algorithm #causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... Treatment: ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... • Pruritis ... platelets - WBC ... Hodgkin Lymphoma Treatment ... #oncology #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... processes: • Systemic ... • Painful or pruritic ... Antiphospholipid syndrome ... #rheumatology #