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hematology algorithm dermatology differential generalized mds activation aplastic cerebritis classification erythematosus hodgkins leukemia lupus lymphoma macrophage mas myelodysplasia neurology primary
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... and Primary Causes ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #primary #secondary
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #secondary #systemic ... #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... (CNS) dysfunction ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... sweats, bleeding • Pruritis ... - infiltrates (anemia ... bone marrow and secondary ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... • Pruritis ... platelets - WBC ... Hodgkin Lymphoma Treatment ... #oncology #management
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