45 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... procedures - Infection ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... #Workup #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... diagnosis #management #hematology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... diagnosis and treatment ... MRI lesions and clinical ... #neurology #noninflammatory ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... Diagnosis: Infection ... diagnosis #management #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... bile ducts Differential ... fungal, viral infections
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... • Improve the symptoms ... Anemia #oncology #hematology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... - Emergency Causes ... axial T1 and T2 Treatment ... #differential # ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... Guillain-Barre Clinical ... - NORMAL CSF WBC ... #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Clinical Presentation ... Blood smear - RBC ... younger pts) Differential ... hemolytic #anemia #hematology