11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Increased Requirement (e.g ... Pregnancy) - Low ... Myelodysplastic Syndromes ... #Causes #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Syndrome (Hemolysis ... #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... syndrome - ... Hemolytic uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... biliary obstruction, HELLP ... Syndrome, Celiac ... Malignancy, 1° PBC ... Toxic: Medication, Pregnancy
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... • Gilbert's syndrome
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
preeclampsia patients • HELLP ... : Syndrome of hemolysis ... so have high clinical ... htn #obstetrics #cardiology ... #differential #
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
109 mm Hg) with clinical ... Hypercalcemia, Cushing's syndrome ... White-coat syndrome ... Pregnancy-associated ... Guillain-Barre Syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome