17 results
diagnosis hematology management differential leukemia algorithm cll lymphocytic lysis tls acromegaly anemia aplastic apml calcium cell cirrhosis classification cppd deposition
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... • Pathophysiology ... diagnosis #management #hematology
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... Initial workup ... of the above Treatment ... diagnosis #management #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... if high risk if WBC ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... patients with minimal tumor ... Vmphocytosis on routine CBC ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... Malnutrition due to chronic ... • Tumor-induced ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
else is driving RBC ... delivery/sensing) vs tumor ... normal/high - Chronic ... kidneys) - Some tumors ... you’ll do a good workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Leukemia #Hematology ... #Oncology #Diagnosis
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