18 results
diagnosis differential management algorithm chronic disorders monoclonal myelodysplastic aplastic cancer common cvid erythematosus extravascular gammopathies gap globulin hemeonc hemolysis hemolytic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... adult T cell leukemia ... #Lymphocytic #Leukemia ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... - infiltrates (anemia ... Leukemia (CLL) ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Transformation to large cell ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... #MDS #Diagnosis ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) (e.g. lupus, CLL ... Hemoglobinopathies (e.g. sickle cell ... differential #diagnosis #hematology ... #anemia
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
common - T Cell ... ~10% - B-Cell ... Treated Like Acute Leukemias ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
marrow plasma cell ... , B and T cell lymphoproliferative ... diseases, CML, ... MGUS #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... changes), high MCV anemia ... not required in all ... #Workup #hematology
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