12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... prevention (statin for CVA ... #neurology #rheumatology ... #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... CMV) • Epstein-Barr ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +GI+CVS+joints) ... • Amyloidosis (CVS ... Paraproteinemias #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
severe community-acquired ... DDX - Other causes ... infections (Epstein-Barr ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Common organisms ... and cauda equina TREATMENT ... #Syndrome #diagnosis ... #management #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
of age • Most common ... skin injury) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... cord • Guillain-Barre ... axial T1 and T2 Treatment ... diagnosis #causes ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Autoimmune disease, Cancer ... being the most common ... Reversible course Differential ... #diagnosis #management ... #neurology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Diagnosis Framework ... Infection or cancer ... II ○ Susac’s syndrome ... trauma ○ MS, CVA ... Labyrinthitis ○ Epstein-Barr
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
definition: Most common ... with systemic, neurologic ... very remarkable w/differential ... them, but urgent rheumatology ... #Management