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anemia oncology algorithm classification hemolytic workup abg acid acidbase agglutinin approach bloodgas cerebritis chronic cll cns coagulation cold dic disseminated
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss ... Deficiency • Aplastic ... Anemia of Chronic Disease ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... plateletcount), peripheral blood ... (CVID, WAS), (neurologic ... Diagnosis #Causes ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Normal Blood Smear ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... including white blood ... cell aplasia DOI ... #diagnosis #causes ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... sensitize red blood ... the RBCs causing intravascular ... hemolytic #anemia #hematology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... Diagnosis: Causes ... sedation, narcotics, CVA ... restrictive lung disease ... #Summary #Nephrology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... • Anemia • Aplastic ... Myeloproliferative Disease ... count with differential ... #diagnosis #hematology
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