13 results
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory ... conditions such as disseminated ... #Microscopy
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Smear #Analysis ... #hematology #microscopy ... interpretation #clinical
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... - Peripheral Blood ... Smear ↑ abnormal
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
A complete blood ... count (CBC) should ... as a peripheral smear ... microangiopathic hemolytic ... LaboratoryFindings #Disseminated
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... of Peripheral blood ... smear - Shows schistocytes ... from ischemia WBC ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... anemia in which ... phenomenon include disseminated ... #Clinical #Path ... #Smear #Schistocytes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
(RBC = red blood ... ordering a peripheral smear ... Hemorrhage or hemolysis ... of the initial work-up ... Homocysteine #Algorithm #Workup
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... anemia • Cold ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... ABO incompatible blood ... organ damage Clinical ... venipuncture sites Laboratory ... • Peripheral smear
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... Leukemia #diagnosis #workup