27 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Chronic ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Who? ... to 8 years Clinical ... microorganisms or who ... autoimmune hemolytic anemia ... ) • Systemic granulomatous
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Occurs on the arms ... Most common extra cutaneous ... Treatment: - Systemic ... #diagnosis #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Who? ... Marrow Failure • Chronic ... Myeloproliferative Disease ... factor (GCSF) treatments ... #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... vasculitis) • Cutaneous ... (Clinical Dx). ... Arthritis, AS Treatment ... Recurrent and chronic