48 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail ... Iron deficiency anemia ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Hepatosplenomegaly and generalized ... with leukopenia, anemia ... Treatment: • Corticosteroids
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Diagnosis and Treatment ... Algorithm Matthew ... Ho, MD PhD @MatthewHoMD ... #HES #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Cholestatic liver disease ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency Anemia ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... TPN Matthew Ho ... #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... reactions Matthew Ho
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Who? ... to 8 years Clinical ... microorganisms or who ... autoimmune hemolytic anemia ... ) • Systemic granulomatous
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Overview Who ... Clinical Presentation ... Treatment: ... than 50 years who ... #oncology #hematology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Diagnosis: • Based on clinical ... antibodies are ... and mild generalized ... - Improves clinical ... MG who are younger