18 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Diagnosis and Treatment ... Algorithm Matthew ... Ho, MD PhD @MatthewHoMD ... #HES #Hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Clinical Features ... Can begin in arms ... Absent Reflexes: Arms
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... reactions Matthew Ho
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Syndrome #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... tumour B cells are ... Classification #pathophysiology ... #Hematology #Diagnosis ... #algorithm
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Overview Who ... Aplastic Anemia Clinical ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... than 50 years who
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... laboratory tests, which are ... reevaluate patients in whom ... and to adjust treatment ... Thrombocytopenia #Algorithm
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Who? ... to 8 years Clinical ... microorganisms or who ... infections (Epstein-Barr ... syndrome, HIV)
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... hyperparathyroidism Treatment ... • Arrhythmias are ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Who? ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology