14 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
- Differential ... Diagnosis • ... Trauma: Shock liver ... Metabolic: Wilson Disease ... #hepatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Kawasaki disease ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash ... #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Anticoagulants (Warfarin ... deficiency • Liver ... mountain spotted fever ... • Drug reactions ... #Diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... AIHA, Transfusion reactions ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... #Diagnosis #hematology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... Mediterranean fever ... Ascites #Causes #diagnosis ... #differential # ... hepatology #SAAG
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
NASH, Chronic ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Fever >38.5 2. ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • NASH, Chronic ... #hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... maculopapular rash ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... Petechial or purpuric rash ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology