35 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... fraction < 20% Differential ... solid cancers • Systemic ... #diagnosis #management
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... • Cholestatic liver ... disease Creatinine ... Myelodisplastic syndrome ... Diagnosis #Algorithm
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
discoloration) • Liver ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Petechial or purpuric rash ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
33% of healthy adults ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
usually to TEN in adults ... Kawasaki disease ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... /splenomegaly, liver ... #rheumatology # ... management
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... maculopapular rash ... episode (30%) Systemic ... #diagnosis #management
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Hypertension - Differential ... Renal Parenchymal Diseases ... Sympathetic nervous system ... HTN #Secondary #Nephrology ... #Differential #