18 results
coagulation causes pt rheumatology treatment abnormal algorithm aptt blood hepatology product prolonged reactions syndrome activation adultonset arterial bleeding bruising chemistry
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Medications - Heparin ... , LMWH, warfarin ... ) • Advanced Liver ... table #comparison #diagnosis ... #hematology #deficiency
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
or antagonism (warfarin ... inhibitor • Liver ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology ... #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology ... #nonpalpable #dermatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Diagnosis and Management ... hemoglobin/hemosiderin, Hepatic ... #Diagnosis #Management ... #Algorithm #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Supratherapeutic warfarin ... • Reduced liver ... #differential # ... hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early warfarin therapy ... Early liver disease ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
and Management ... Management: • ... ), reverse any warfarin ... and management ... #Hematology #HemeOnc
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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