14 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Reversal Agents - Warfarin ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... #Medications #Pharmacology ... Pathophysiology #Mechanisms #DOAC ... #Hematology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
commonly used anti-coagulation ... Enoxaparin - Warfarin ... #medications #doac ... #comparison #table ... #management #drugs
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Heparin, LMWH, warfarin ... , DOACs (e.g. direct ... Summary #table #comparison ... #diagnosis #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Managing warfarin ... hemorrhage, while under-coagulation ... #management #algorithm ... #pharmacology # ... decisionaid #cardiology #hematology
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Switching from DOAC ... to Warfarin (Bridge ... to DOAC (No Bridging ... anticoagulation #pharmacology ... #management #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Anticoagulants (Warfarin ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... anticoagulant #hematology ... #management #pharmacology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic #Myopathy #Comparison ... #Managment #algorithm ... #Rheumatology # ... Differential