22 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Prednisone 5mg/kg ... #APML #diagnosis ... #management #hematology ... #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... malignancies Treatments ... with Ca only if EKG ... #TLS #oncology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
Equivalents on ECG ... point • De Winter syndrome ... sign B - Deeply ... #Equivalents #ECG ... #EKG #diagnosis
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Algorithm Red ... papilledema • Horner syndrome ... (e.g., fever, myalgia ... CNS infection (e.g ... #Algorithm #neurology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
- Differential Diagnosis ... Algorithm Idiopathic ... ), Heme malig (AML ... inflammatory disease: e.g ... #Algorithm #allergy
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Management Summary Diagnostic ... present, symptoms, signs ... transformation into AML ... • Treatment algorithms ... #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Algorithm Endocrine ... Neoplastic / Hematologic ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual ... #treatment #MS