17 results
Wellens' Sign: LAD-T Wave Inversion 
Life threatening T wave inversions in precordial leads. Often V2-V3 
Specific
Wellens' Sign: LAD-T ... Serial EKGS in pts ... #Wellens #Sign # ... EKG #ECG #Electrocardiogram ... #Diagnosis #Cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
point • De Winter syndrome ... sign A - Biphasic ... sign B - Deeply ... #EKG #diagnosis ... differential #cardiology #electrocardiogram
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
incidentally during medical ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment:
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Seizures • Altered mental ... Etiology: • Pathophysiology ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
joint and spine, & medium ... and lower jaw Treatment ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Involves large and medium ... systemic sx + signs ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs