22 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Increased Requirement (e.g ... • Small Bowel Disorder ... Macrocytosis, Target Cells ... Liver Function Tests
Pulmonary Hypertension Groups - WHO Classification
Group I - Vascular remodeling of pulmonary arteries
 • Idiopathic, HIV,
connective tissue disorders ... chronic hemolytic anemia ... , thyroid disorders ... , sickle cell anemia ... #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... lymphoproliferative disorders ... . sickle cell disease ... #hematology #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider sickle cell ... Consider RBC membrane disorder ... #Algorithm #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... , ANA (e.g., SLE ... changes), high MCV anemia ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... malignancies - B-cell ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... ... laboratory tests ... (parkinsonian signs ... Differential #Subtypes #Classification ... #Workup #Diagnosis