16 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side ... #Inhibitors #Pharmacology ... #Summary #DM2 #
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 ... #Pharmacology #
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... linagliptin) 5 mg DPP4 ... with only few side ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
mechanism of action, side ... #pharmacology #dm2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side ... Toxicities: • GI side ... #Metformin #Pharmacology ... #Summary #DM2 #
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... in CKD Common Side ... Sulfonylureas #Pharmacology ... #Summary #DM2 #
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
(Adlyxin) • DPP ... by inhibiting DPP ... Diabetes #Management #pharmacology ... #DM2 #DMII #Classification
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... mL/minute/1.73 m2 ... of use) Common Side ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 #
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... Dosing #Diabetes #DM2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... Diabetes #Mellitus #DM2 ... #Medications #pharmacology