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hematology management a4c cardiology cell constrictive disease echocardiogram gammopathy hemeonc hemophagocytic hlh igg4 lymphohistiocytosis macrophage mas mgrs monoclonal oncology pericarditis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... response to treatment ... Glucocorticoids (0.6 mg/kg ... management #phenotypes #workup ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Fever is the main clinical ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Rheumatology
Constrictive Pericarditis on Echocardiogram A 55-year-old female marathon runner presents to clinic w/ 6-months of worsening breathlessness
had gained 15 kg ... echocardiogram to workup ... expiration not meeting diagnostic ... Echocardiogram #a4c #pocus ... #clinical #cardiology
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 Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... by uncontrolled activation ... Clinical Presentation ... Treatment Approach ... #Management #Hematology
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Clinical Clues: ... Workup: • Kidney ... Complement pathway activation ... microangiopathy Treatment ... #Significance #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... red bone marrow, e.g ... Diagnosis? ... Bone marrow Treatment ... #Workup #Hematology
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