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diagnosis management hematology causes druginduced thrombocytopenia activation anemia behcet bruising classification comparison dermatology disease extravascular hemolysis hemolytic intravascular macrophage mas
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... Workup: - ANA ... Workup: - ANA ... #table #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Associated - SLE ... #Differential # ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... SJIA], systemic lupus ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL ... Acute bacterial and
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... thrombocytopenic purpura ... usually IgG) (e.g. lupus ... disease, Copper and ... Extravascular #Causes #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... inflammation Others: • Lupus ... such as systemic lupus ... SLE) • Urinalysis ... #diagnosis #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(systemic lupus ... - DIC (disseminated ... Meningococcal and ... , SLE - Scurvy ... pediatrics #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
lesions, palpable purpura ... Behcet disease) Differential ... Oral aphthae : SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... with interleukin (IL ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
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