39 results
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Involvement, Spares DIP, Carpal ... Tunnel, Sicca Syndrome ... Disease, Rheumatoid Vasculitis ... #diagnosis #rheumatology ... #signs #symptoms
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE, RA ... Skin Findings: ... Disease • Cogan syndrome ... #rheumatology #
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
Differential Diagnosis: Rheumatologic ... systemic sclerosis, RA ... , SLE, Sjogren syndrome ... Hypothyroidism - Carpal ... tunnel syndrome
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... gangrenosum • IBD • RA ... Antiphospholipid-antibody syndrome ... • Vasculitis ... differential #diagnosis #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
small joints (wrists ... boggy" joints, esp carpal ... fingers, radial wrist ... Extra-articular signs ... pathophysiology #signs
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Hyperviscosity Syndrome ... - 10% SLE or RA ... reticularis & skin ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Rheumatoid factor - RA ... La) - Sjogren's syndrome ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... diagnosis #table #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Scleritis - RA ... Nodules • RA ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... differential #diagnosis #rheumatology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Dry coarse skin ... peripheries, Carpal ... timel syndrome, ... Goitre), Dry skin