12 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
>>> MPA > eGPA ... ): eGPA, MPA >>> ... #differential # ... diagnosis #algorithm ... #rheumatology
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
Known Cause - Differential ... Diagnosis Exposure ... Granulomatous DX with Vasculitis ... : GPA, EGPA • ... lung #disease #pulmonary
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... (AAV): GPA (granulomatous ... polyangiitis), MPA ... subglottic stenosis) in GPA ... #diagnosis #management
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated Vasculitis ... polyangiitis (GPA ... #differential # ... diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
capillaritis • EGPA ... > PR3 60% • GPA ... • ANCA (Dx: GPA ... differential #diagnosis ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... polyangiitis - EGPA ... - GPA Cutaneous ... #dermatology #rheumatology ... diagnosis
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Diagnosis Framework ... Kaposi's sarcoma • Rheumatologic ... Autoimmune: ANCA-Assoc vasculitis ... (GPA > EGPA, MPA ... #Diagnosis #pulmonary
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - GPA - EGPA ... - MPA • CTD ... #Diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... Diagnosis: Vasculitis ... #Polyangiitis #GPA
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... progressive) EGPA ... > PR3 60/ GPA ... Diagnosis #Rheumatology