24 results
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... flexion test ... • + Tinel sign over ... #Diagnosis #pathophysiology ... #msk
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... disorders (e.g. autoimmune ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Causes #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... adults in the west ... Physical Exam/Signs ... Diagnosis: • ... workup #oncology #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Autoimmune diseases ... Atopic diseases, Chronic ... spontaneous urticaria, Chronic ... Cold #Urticaria #diagnosis ... #rheumatology #
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... thickening, distal to elbows ... /wrists and knees ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
(vasculitis / autoimmune ... Primary: - CML ... Hypereosinophilic Syndrome ... - Chronic Eosinophilic ... #Causes #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... Laboratory Tests ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... (older) • Autoimmune ... test #cold # ... hemolytic #anemia #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... Rheumatologic Disease ... #Differential #Diagnosis ... #MSK #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
sex • Metabolic syndrome ... knees, fingers, wrist ... , elbow • Nocturnal ... double contour sign ... management #treatment #rheumatology