7 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia ... #symptoms
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
compression of nerve ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... - Emergency Causes ... #neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... threat Cranial Nerves ... • Examine for signs ... Casey Albin MD @ ... #PhysicalExam #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Causes: 1. ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... disorders #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... brain and/or optic nerve
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
multiple spinal cord ... - Causes progressive ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... activity between nerve
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Recurrent Falls Core ... presyncope, exertional symptoms ... positive Romberg sign ... Examples: - Dementia ... #Neurology