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diagnosis oncology differential causes chronic cll lymphocytic activation aplastic hemeonc hemolytic macrophage mas mds myelodysplasia myelodysplastic syndrome syndromes testing thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... #Causes #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... or thrombocytopenia ... or thrombocytopenia ... #oncology #hematology ... hemeonc #diagnosis #management
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... ARUPLabs #Hemolytic #Anemia ... #workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Neutropenia, anemia ... , thrombocytopenia ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... infections/fevers • Thrombocytopenia ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... with leukopenia, anemia ... , and thrombocytopenia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Workup: • Complete ... Syndromes #diagnosis #hematology
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