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diagnosis differential management rheumatology oncology algorithm infectiousdiseases syndrome arthritis dermatology hemophagocytic hlh lymphohistiocytosis pathophysiology sweet aids anemia approach bandemia blastomycosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD ... , Celiac disease
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
Diagnosis and Workup ... Summary Use a positive ... Routine stool cultures ... Rule out celiac disease ... inflammatory bowel disease
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... microglobulin Treatment ... ’s lymphoma or acute ... #oncology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... • Autoimmune diseases ... odds of having positive ... overlook severe infections ... neutrophil #WBC #CBC #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... to 12 weeks for acute ... extrapulmonary disease ... becomes a yeast cell ... have positive blood
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... Send for cell count ... , culture, look ... cutoff... >10K is ... #approach #workup
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
inflammatory disease ... , or pregnancy or ... gastrointestinal tract infection ... Excellent response to treatment ... rate >20 mm/h; positive
13 Dangerous Causes of Headache: - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
head in dependent position ... at home or at work ... ) - acute angle ... temporal (giant cell ... preeclampsia: late pregnancy
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... rare, Malar rash is ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... presents as an acute ... Low or absent NK cell ... : • Infection ... #hematology
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