11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute Fatty ... (AFLP) Three syndromes ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... : • Defect in fetal ... = nonspecific (nausea ... Preeclampsia, HELLP ... Pregnancy #hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... plasma exchange 2) Fatty ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... , no necrosis HELLP ... #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... Others #LFTs #Hepatology ... #Algorithm #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... - Drugs - Pregnancy ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular ... Causes of Acute ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... metastasis • Fatty ... liver of pregnancy ... #causes #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... non-alcoholic fatty ... liver disease; ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver