55 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in GBA1 gene Clinical ... Yann Nguyen @YannNgyn ... Disease #Diagnosis #Signs
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
Tree in Bud Sign ... The Tree-in-Bud sign ... Bud #TreeInBud #Sign ... #diagnosis #clinical ... radiology #ChestCT #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... vara • Coxa valga ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... BPM INFECTIOUS CAUSES ... • Drug Fever CLINICAL ... limited predictive value ... #Fagets #Sign #Pulse
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Cullen's sign. ... This sign is named ... Pathophysiology: ... The sign indicates ... necrosis, ectopic pregnancy
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... • Urinary and fecal ... Syndrome #MSK #pathophysiology ... diagnosis #symptoms #signs
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... Passive neck flexion causes ... While the pathophysiology ... #Meningitis #Clinical
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... : • Defect in fetal ... = nonspecific (nausea ... #Fatty #Liver #Pregnancy
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... significant portal HTN Signs ... obstruction) • Lack of signs ... Post-Hepatic: • Cardiac causes ... Fatty liver of pregnancy
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Alzheimer's (99% of cases ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs