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algorithm liver hepatitis hypertension lfts obstetrics pathophysiology workup abnormal alkaline alp arterial ascites biliary cholangitis cirrhosis comparison elevation embolism enzymes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... : • Defect in fetal ... = nonspecific (nausea ... infiltration) Differential ... Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... - Drugs - Pregnancy ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... Others #LFTs #Hepatology ... #Causes
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... metastasis • Fatty ... liver of pregnancy ... #Diagnosis #causes ... #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... - Acute fatty ... liver of pregnancy ... #diagnosis #differential ... #hepatology #SAAG
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... melanoma, myeloma • Pregnancy ... #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Diagnosis Framework ... Myeloproliferative disease ... Intravenous Drug Use • Pregnancy ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... cholestasis of pregnancy ... #workup #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... non-alcoholic fatty ... liver disease; ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
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