9 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... Syndrome and Acute ... coagulation defects. 1) HELLP ... AFLP #obstetrics #hematology ... #diagnosis #table
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... Preeclampsia, HELLP ... #hepatology #obstetrics
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... and hemorrhage Acute ... #hepatology #obstetrics ... #differential #diagnosis ... #icp #HELLP #AFLP
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... Sweet Syndrome (Acute ... inflammatory disease, or pregnancy ... Abnormal laboratory values ... #Hematology #Dermatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #Differential #Diagnosis ... #algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... Treatment: - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... • Cirrhosis/acute ... Fatty liver of pregnancy ... #causes #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #differential #diagnosis ... #algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presents as an acute ... or subacute febrile ... Diagnosis via genetic ... management #treatment #hematology