23 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... Fatty Liver of ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... AFLP #obstetrics #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... headache, malaise) → Acute ... #Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... post-partum • Typical clinical ... and hemorrhage Acute ... post-partum • Typical clinical ... #hepatology #obstetrics
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Autoimmune hepatitis, Acute ... Toxic: Medication, Pregnancy ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... ACLF) Clinical Guidelines ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... melanoma, myeloma • Pregnancy ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... #differential #Hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... • Cirrhosis/acute ... sarcoidosis) • Liver ... of pregnancy ... Diagnosis #causes #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Cirrhosis • Pregnancy ... immunosuppression • Acute ... > 3 mg/dL) or acute ... liver failure ... Indications #management #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... pregnancy 3. ... #differential #hepatology