10 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
- Biliary tree ... Transaminase, ALP ... ≥ 2x ULN R Value ... ) / (ALP / ULN ALP ... #diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... or AST > ALP): ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... Cholestatic Pattern (ALP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ) Elevation - Differential ... Diagnosis Algorithm ALP ... - Increased ALP ... #Elevation #Differential
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • AST/ALT elevation ... • R value = (ALT ... Transaminitis #diagnosis #differential ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... melanoma, myeloma • Pregnancy ... GGT/5-NT: ↑ - ALP ... hemolysis) • ALP ... diagnosis #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
(AFLP) Pathophysiology ... : • Defect in fetal ... infiltration) Differential ... iMedEducation #AFLP ... #hepatology #obstetrics
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... (AFLP) • Onset ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
magnitude of enzyme elevation ... include extrahepatic biliary ... ALP, alkaline phosphatase ... #LFTs #Abnormal ... #Algorithm #Hepatology