9 results
diagnosis hematology algorithm anemia causes hemolysis hemolytic injury liver acute agglutinin bandemia classification cold disease erythematosus extravascular hepatitis hodgkins intravascular
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... diagnosis #neutrophil #WBC ... #CBC #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... 2) External (RBC ... Membrane): - Autoimmune ... 3) Internal (RBC
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, PBC, PSC, IgG4 ... stone, Malignancy, PBC ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... vasculitis, malignant hypertension ... • Unusual RBC ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... Blood smear - RBC ... CLL (older) • Autoimmune ... younger pts) Differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Hodgkin Lymphoma - Clinical ... platelets - WBC ... Immunohistochemical studies (to differentiate ... classification #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... disease • Non-autoimmune ... Frank nephritis (hypertension ... titers > 1:80 • CBC
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