12 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... : • Defect in fetal ... infiltration) Differential ... Hepatitis, Preeclampsia ... #hepatology #obstetrics
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
#hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Check Acute viral hepatitis ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... #differential # ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... Fatty liver of pregnancy ... #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... gastrointestinal bleed, hypotension ... #diagnosis #Alcoholic ... #hepatology #criteria
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... >1.5, and both values ... gastrointestinal bleed, hypotension ... #Diagnosis #Hepatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... Diagnosis Approach ... previously stable values ... 109 mm Hg) with clinical ... Pregnancy-associated
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Peritoneum Portal hypertension ... - Alcoholic hepatitis ... fatty liver of pregnancy ... #differential # ... hepatology #SAAG