10 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
: • Defect in fetal ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #Injury #Differential ... Acute #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #HELLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... of pregnancy ... Diagnosis #causes #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... gastrointestinal bleed, hypotension ... ) or metabolic liver ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... gastrointestinal bleed, hypotension ... ) or metabolic liver ... #Diagnosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... #differential # ... diagnosis #algorithm #hepatology
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
pits <100k), ↑ liver ... preeclampsia patients • HELLP ... hemolysis, elevated liver ... diagnosis so have high clinical ... obstetrics #cardiology #differential
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Peritoneum Portal hypertension ... - Alcoholic hepatitis ... of pregnancy ... Causes #diagnosis #differential ... #hepatology #SAAG