9 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty ... Liver of Pregnancy ... (AFLP) Three syndromes ... obstetrics #hematology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... hypoglycemia, encephalopathy ... iMedEducation #AFLP
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... and hemorrhage Acute ... Pregnancy (AFLP) ... coagulopathy, encephalopathy ... #differential #diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Mixed - Check Acute ... INR > 1.5 • Encephalopathy ... • Gilbert's syndrome ... #chemistry #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... • Gilbert's syndrome
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Wernicke Encephalopathy ... - Acute B1 (Thiamine ... - Caine Criteria ... Hyperemesis of pregnancy ... development of Korsakoff syndrome
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... thrombocytopenia, hepatic encephalopathy ... and hepatorenal syndrome ... • Cirrhosis/acute ... of pregnancy
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential Diagnosis ... utilization: - Pregnancy ... • Wernicke's Encephalopathy ... liver failure: ... #Differential #Diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... inflammatory disease, or pregnancy ... Abnormal laboratory values