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diagnosis differential rheumatology neurology algorithm barre dermatology treatment autoimmune blood cerebritis chronic classification cns cryoglobulinemia cryoglobulins erythema erythematosus fatigue gbs
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Drugs (antibiotics e.g ... Sarcoidosis or Lofgren's syndrome ... Viral: HSV, EBV, HIV ... Differential #Diagnosis #Dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG ... #diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Hepatitis • HIV ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... Electrodiagnostic studies (Ex EMG ... #Barre #Syndrome ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... HBV infection, HIV ... tissue disorder (e.g ... classification #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... #Rheumatology # ... diagnosis #management ... #Dermatology
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