10 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... or if a primary hematologic ... disorder is suspected ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
altered colour e.g ... . e.g. psoriasis ... a generalized disorder ... #Diagnosis #Dermatology ... #Nomenclature #Atlas
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT ... Testosterone - Coumadin skin ... thrombosis in young ... Venous #Arterial #pathophysiology ... #hematology #differential
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... HBV infection, HIV ... (e.g. systemic
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rule out other causes ... antiinflammatory properties e.g ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... • TTP, HUS and HIT ... #hematology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
and pruritus (e.g ... temples, upper lip ... honey-colored crusts ... Varies with site, (e.g ... ; pruritis #dermatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... infections with skin ... Extremely rare - HIV ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology