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Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Differential Diagnosis Secondary ... Chronic inflammatory disorders ... (e.g. autoimmune ... #hematology #secondary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... Ig A vasculitis/HSP ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... or if a primary hematologic ... disorder is suspected ... #Workup #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... NailDisorders #Systemic #Secondary ... #dermatology #Differential ... Diagnosis #Algorithm #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
, Seizure disorders ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... APS), Secondary
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
altered colour e.g ... associated with secondary ... . e.g. psoriasis ... a generalized disorder ... #Diagnosis #Dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... Type III Often Secondary ... (e.g. systemic
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... , eg, cyclic neutropenia ... drug reactions - Secondary ... therapies-common - Secondary ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... • TTP, HUS and HIT ... #hematology
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