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diagnosis management hematology betadglucan fungal galactomannan neurology agammaglobulinemia aspergillus barre biomarkers cerebritis checklist cns comparison cryofibrinogenemia differential disorders erythematosus falsepositives
Management of Jehovah's Witness patient in ICU Clarify which products may be used - Discuss
Witness patient in ICU ... Clarify which products ... early & document (e.g ... hemostatic agents (e.g ... #CriticalCare #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Risks factor for HIV ... plateletcount), peripheral blood ... smear, HIV/HCV ... function test, ANA (e.g ... #Workup #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... Causes purpura & ... Blood products contain ... Extremely rare - HIV
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
albumin, or other blood ... products - ... formulations (e.g ... beta-glucans (e.g ... products -
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... which can plug blood ... cryoglobulin (CG ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
> Inability to produce ... all classes of ... plasma cells in blood ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... normal CSF white blood ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... intensive care unit (ICU
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
formulations (eg ... False positives: Pip ... Penicillium), Frozen ice-pops ... GVHD), Certain blood ... products #BetaDGlucan
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