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diagnosis differential hematology management classification neurology workup acidosis arthritis autoimmune barre cerebritis cns conditions cryofibrinogenemia cryoglobulinemia cryoglobulins disease disorders elevation
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Risks factor for HIV ... plateletcount), peripheral blood ... smear, HIV/HCV ... function test, ANA (e.g ... #Workup #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... tissue disorder (e.g ... classification #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
disease, Vasculitis (e.g ... arteritis • Bloody ... Heberden's nodes (DIP ... Bouchard's nodes (PIP ... differential #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... cryoglobulin (CG ... processes: • Systemic ... cryoglobulins • Negative causes ... • TTP, HUS and HIT
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... by excretion (e.g ... its metabolism (e.g ... of Circulatory System ... Ethylene glycol - HIV
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... normal CSF white blood ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... intensive care unit (ICU
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Extremely rare - HIV
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... : • Complete blood ... inflammatory disease (e.g ... Chemistry profile (e.g
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... weakness + atrophy- Hip ... • Conduction system ... statins - probably caused
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