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diagnosis management differential hematology symptoms neurology syndrome treatment workup algorithm barre clinical disorders guillain psychiatry thrombocytopenia agammaglobulinemia als amyotrophic anesthesia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Quinidine • HIT ... Foreign Surface (e.g ... #Hematology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
the knees and hips ... Passive neck flexion causes ... While the pathophysiology ... for the hip/knee ... In very young (less
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 Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
most common in young ... to the femur ( e.g ... vehicle accident in young ... #differential #causes ... #pathophysiology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... tissue expansion (e.g ... #FeedbackLoop #endocrinology ... #pathophysiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Risks factor for HIV ... peripheral blood smear, HIV ... function test, ANA (e.g ... patients if the cause ... #Workup #hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
, e.g. central line ... pericardiocentesis kit (eg ... examination and vital signs ... • Identify tip ... immediately to left of tip
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
risk factors (eg ... hypertension (eg ... hypertension (eg ... renal bruit or signs ... Vasculitis • Endocrinologic
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