27 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
the knees and hips ... Passive neck flexion causes ... While the pathophysiology ... for the hip/knee ... In very young (less
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
most common in young ... to the femur ( e.g ... vehicle accident in young ... #differential #causes ... #pathophysiology
A practical guide to starting levothyroxine therapy
Calculate full replacement dose: 1.6 mcg/kg/day
Young, otherwise healthy patient:
 •
replacement dose: 1.6 mcg ... /kg/day Young, ... Start at 25-50 mcg ... starting #management #endocrinology ... #pharmacology #
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... tissue expansion (e.g ... #FeedbackLoop #endocrinology ... #pathophysiology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... side effects (e.g ... #Metformin #Pharmacology ... DM2 #diabetes #endocrinology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
, e.g. central line ... pericardiocentesis kit (eg ... examination and vital signs ... • Identify tip ... immediately to left of tip
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Hepatitis • HIV ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Diagnosis #Algorithm #causes
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... side effects (e.g ... not definitively cause ... Receptor #Agonists #Pharmacology ... DM2 #diabetes #endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
risk factors (eg ... hypertension (eg ... hypertension (eg ... renal bruit or signs ... Vasculitis • Endocrinologic
This is a parasternal long axis view of a young patient presenting with 3 days of
axis view of a young ... x-ray and and ECG ... ultrasound got him ... In this case, the