14 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
(e.g low cardiac ... carrying capacity (e.g ... cannot use oxygen (e.g ... #diagnosis #causes ... #pathophysiology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... Tuberculosis • Epstein-Barr ... Chronic Obstructive Pulmonary ... Disease Neurologic ... • Drug Abuse (e.g
Hypoxemic Respiratory Failure - Differential Diagnosis Framework
DECREASED INSPIRED OXYGEN
 • Low PATM Can decrease first part
High altitude (eg ... respiratory drive due to neurologic ... direction leads to hypoxemia ... Intrapulmonary shunting (eg ... intracardiac shunting (eg
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG ... management #treatment #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Risks factor for HIV ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Polycythemia - Acquired Causes ... : • Hypoxia-driven ... : Cardiac/pulmonary ... Paraneoplastic (e.g ... Diagnosis #Algorithm #hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... diagnosis #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... coma - Pulm: Hypoxia ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
usually: - hypoxemia ... by excretion (e.g ... its metabolism (e.g ... output - Acute pulmonary ... Ethylene glycol - HIV
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #