12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Prednisone 5mg/kg ... sepsis), PE, DAH, CHF ... organ dysfuxtion, ICU
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... unless worrisome EKG ... diagnosis #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... and cauda equina TREATMENT ... intensive care unit (ICU
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Pathophysiology ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Significance (ICUS ... factor (GCSF) treatments ... factors (examples: G-CSF ... #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... • EEG: With persistent ... the underlying cause ... • Treatment of ... with AEDs until cause
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
ECG is vital while ... acute coronary syndrome ... the determined cause ... #heartfailure #chf ... #criticalcare #icu
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... cardiomyopathy (e.g ... hemodynamics (e.g ... LVEF recovery (e.g ... teratogenic GDMT meds (e.g