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diagnosis management differential sclerosis als arteritis autoimmune emergency gca giantcell headache hemeonc hemophagocytic hlh hypertension indications lateral leukostasis lymphohistiocytosis lysis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... Manifestations #diagnosis #neurology ... #symptoms #signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
risk factors (eg ... hypertension (eg ... hypertension and signs ... hypertension (eg ... renal bruit or signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
of diagnosis (e.g ... Self-limiting, chronic but stable ... : (distinct symptoms ... Diagnosis #Management #Signs ... #Symptoms
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
Emergent Causes ... carbon monoxide (eg ... living conditions (eg ... vascular diseases (eg ... of the body - Young
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... GCA #Temporal #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... and Symptoms: ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused ... Myositis #Myopathy #rheumatology
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