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diagnosis differential abnormal anemia aptt hepatology prolonged pt bleeding bruising chronic classification comparison deficiencies deficiency dermatology dili druginduced elevatedmcv fatigue
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) • Advanced Liver ... Autoimmune disorders (e.g ... Deficiencies #Summary #table
Liver Mass - Differential Diagnosis Algorithm Benign Cystic • Cyst • Polycystic Liver Disease • Caroli's
Diagnosis Algorithm ... • Metastases (e.g ... #Mass #Hepatology ... Differential #Diagnosis #Algorithm ... #Causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Chronic Disease (e.g ... Renal Disease, Liver ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... • Reduced liver ... #coagulation
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... Increased Requirement (e.g ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... of information (e.g ... for alternative causes ... vascular disorder (e.g ... #hepatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Renal Failure • Liver ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... discoloration) • Liver ... Systemic #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
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