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diagnosis differential treatment cardiology rheumatology algorithm anesthesia anesthesiology checklist intraoperative pharmacology abnormal aptt clinical comparison dermatology lupus nephrology prolonged pt
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Rare • Drugs (e.g ... • Vasculitis Coagulation ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology ... #coagulation
Vasopressors Table Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... /kg/min - Milrinone ... Vasopressors #Properties #Table ... Pharmacology #Effect #Management
Hypermagnesemia - Etiologies by Mechanism Renal Failure Excessive Mg Administration - Massive PO intake
IV Mg infusion (e.g ... High #Magnesium #Table ... #Causes #Management
Treatment of Stable Narrow-Complex Tachycardia Regular Rhythm: • Attempt vagal maneuvers • Give adenosine 6 milligrams IV
Control rate (e.g ... Treat underlying cause ... Control rate (e.g ... Treat underlying cause ... Tachycardia #Treatment #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Cardiac Stress Testing Exercise: • Everyone who can exercise should! • They must be able to raise
• They must be able ... production to cause ... arrythmias Diagnostics: EKG ... Testing #cardiology #management
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